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Health
Diseases
Lupus
Lupus
is a difficult disease to detect. It can take months maybe
even years for an accurate diagnosis. This is because the
symptoms mimic those of much less serious illnesses. For most
people, lupus is a mild disease affecting only a few organs.
For others, it may cause serious and even life-threatening
problems. As hard as it is to determine if someone has lupus,
it has proven even harder to find a cure.
Currently,
it is estimated that 500,000 to 1.5 million Americans suffer
from lupus with more than 16,000 Americans developing the
disease each year.
So
what is lupus anyway? Lupus is a chronic autoimmune disorder
that affects the skin, joints, blood, and kidneys. A fully
functioning immune system makes proteins to protect the human
body against viruses, bacteria, and other foreign materials.
When someone
has lupus it means that the person's immune
system cannot tell the difference between the foreign
substances and its own cells and tissues. When this happens
the immune system makes antibodies directed against itself.
These antibodies, called "auto-antibodies," react
with the "self" antigens to form immune complexes.
The immune complexes build up in the tissues and can cause
swelling, injury to tissues, and sometimes severe pain.
Who
gets lupus? Scientists believe that there is a genetic
link within families to the disease but it is known that environmental
factors also play a critical role in triggering lupus. Some
of the environmental factors that may trigger the disease
are: infections, certain antibiotics, ultraviolet light, extreme
stress, and hormones. It is still not clear why lupus occurs
more frequently among adult females than males. Lupus is often
called a "woman's disease" even though many men
are affected. Lupus does not discriminate and can occur at
any age. The symptoms of the disease are the same in men and
women.
There
are three types of lupus: discoid, systemic, and drug-induced.
Discoid (cutaneous) lupus is always limited to the skin. It
is identified by a rash that may appear on the face, neck,
and scalp. This rash is usually in the unique shape of a butterfly.
For some people discoid lupus progresses into systemic lupus.
Most of
the time when "lupus" is mentioned, it is systemic
lupus that is being referred to. Systemic lupus is usually
more severe than discoid lupus. Sometimes only the skin and
joints will be involved. For others, the joints, lungs, kidneys,
blood, or other organs and/or tissues may be affected. Since
everyone's immune systems are different, usually no two people
with systemic lupus will have identical symptoms.
Also with
systemic lupus, there may periods of time in which minimal,
if any, symptoms are evident and other times when the pain
and discomfort becomes more intense and more frequent.
The least
common form of lupus is drug-induced
lupus which may occur after the use of certain prescribed
drugs. The symptoms of drug-induced lupus are similar to those
of systemic lupus.
The drugs
most commonly connected with drug-induced lupus are hydralazine
and procainamide.
Not everyone who takes these drugs will develop drug-induced
lupus. The symptoms usually fade when the medications are
discontinued. Drug induced lupus is more common in men who
are given these drugs more often.
What
triggers an attack of lupus? In some patients, exposure
to the sun causes sudden development of a rash and then possibly
other symptoms. In others an infection as simple as a cold,
does not get better, and then complications arise. These complications
may be the first signs of lupus. In still other cases, a drug
taken for some illness produces the signaling symptoms. Sometimes,
the first symptoms and signs develop during pregnancy or soon
after delivery. There are many people who cannot remember
any specific factor. It seems that the triggers can be all
unrelated for the same case of lupus, which makes it difficult
for the person to pinpoint the cause of the flare.
There
can also be times when someone who has been diagnosed with
lupus shows no signs or symptoms at all. These remission periods
are a blessing, but often are short-lived. Lupus patients
know that there is no cure so there is bound to be a flare
up that will be debilitating. Although flares are inevitable,
the earlier they are detected, the more easily they can be
controlled.
So
until a cure is discovered, how is lupus treated? For
the majority of people with lupus, effective treatment can
minimize symptoms, reduce painful swelling, and maintain normal
bodily functions. Preventive measures can reduce the risk
of flares. There are many different treatment approaches because
the specific needs and symptoms of each person and the course
of lupus may vary tremendously. Medications
are often prescribed for people with lupus, depending on the
severity of the individual's case and which organs are involved.
If lupus
is treated early, the patient's chances increase for reducing
the time spent on high doses of drugs and decreasing permanent
tissue or organ damage. One of the most important things that
every person diagnosed with lupus should do is find a lupus
support group. They are everywhere. Find one and get connected!
The prognosis
of lupus is much better today than ever before. There is no
cure for this disease but scientists have learned more in
the past ten years about lupus than in the last hundred.
Take the
shape of the butterfly rash that is so often a symptom of
this life changing sickness and use it to remember that a
butterfly is a sign of new beginnings and new things to come.
Related
Links
also
see -> Arthritis
This
information is intended as reference and not as medical advice.
All treatment decisions should be made by medical professionals.
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